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Emerging Company Profile
Xdynia targeting T type calcium channels in periphery for neuropathic pain
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Xdynia: T type relief
Monday, June 11, 2012
LLC spun out from Tau
Therapeutics Inc. this year to develop oral small molecule inhibitors
of a specific subset of voltage-dependent T type calcium channels that play a
prominent role in pain signal transduction. The approach could offer better
safety and efficacy for neuropathic pain than available drugs.
According to President Yuri
Maricich, up to 60% of patients report no relief from drugs commonly prescribed
for neuropathic pain, such as GABA receptor agonists, selective serotonin and
norepinephrine reuptake inhibitors (SSNRIs) and opiates.
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