BioCentury on BioBusiness,
Emerging Company Profile
HTS with single live cells
Monday, July 9, 2001
Fluidigm Corp. and Axon Instruments Inc. are collaborating to solve
what has been a difficult problem in biology: high throughput screening of single live
eukaryotic cells. The deal will combine Fluidigm's silicone elastomer "rubber
chips" and Axon's ion channel instrumentation. If they are successful, the resulting
chips would enable scientists to do a wider ranger of experiments on single live cells in
a high throughput environment.
In conventional microfluidic chips, liquids can be moved in a variety
of ways. One of the most frequently used is electric forces. But this requires putting
cells in an electrolytic solution, which is not necessarily a natural environment
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