Over the years, the revolutions in biology and computers have come to intersect: genomics and rational drug design, for example, are both made possible by the power of computers. But until recently, the complexity of the body has made animals or human subjects the only useful models for exploring the body's function and its interaction with drugs.

Physiome Sciences Inc. believes it is the only company based on the use of computational models of complex physiological systems to discover, evaluate and develop new drugs and devices. The formation of the company was made possible by the ability to measure and model physiological processes in cells, together with the declining costs of supercomputing. Physiome Sciences's initial focus is cardiology, and models are in development for the pancreas, retina, cochlea and kidney.