The surge in interest in gene therapy after 20 years of trial and error is partly due to better vectors, but some say the real catalyst is the explosion of activity in CAR T cell and gene editing technologies.
A new way of stabilizing trimers of the HIV envelope protein could lead to a more effective HIV vaccine than previous antigens yielded.
The SGC has developed a method for validating antibodies to solve one of the biggest problems of irreproducible research, but there's a growing dispute over who should do the work or pay for it.
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Ixchel's 3D tissue system could predict the clinical success of cancer therapies better than 2D or animal models because it more accurately mimics tumor metastasis.
THE DISTILLERY brings you this week's most essential scientific findings in therapeutics, distilled by Innovations editors from a weekly review of more than 400 papers in 41 of the highest-impact journals in the fields of biotechnology, the life sciences and chemistry. The Distillery goes beyond the abstracts to explain the commercial relevance of featured research, including licensing status and companies working in the field, where applicable.
This week in therapeutics includes important research findings on targets and compounds, grouped first by disease class and then alphabetically by indication.
This week in techniques includes findings about research tools, disease models and manufacturing processes that have the potential to enable or improve all stages of drug discovery and development.