Aduro's STING agonists induce immunity against distal tumors and are among the first compounds to extend cancer immunotherapy to tumor metastases.
TARGETS & MECHANISMS
The shared bone pathology between Gaucher's disease and multiple myeloma could allow Gaucher's therapies to be repurposed for the cancer.
A new type of stem cell offers scalability in vitro and opens the door to growing human tissues in animals.
TRANSLATION IN BRIEF
Loosening attachment of cells to plates can mimic soft agar assays and identify compounds and targets missed by traditional cancer cell screens.
BioCity Scotland has launched an innovation hub to meet the Scottish government's goal of doubling the life sciences sector.
Formula Pharmaceuticals aims to compete in the CAR space with its allogeneic, non-viral technology that uses cytokine-induced killer cells.
THE DISTILLERY brings you this week's most essential scientific findings in therapeutics, distilled by Innovations editors from a weekly review of more than 400 papers in 41 of the highest-impact journals in the fields of biotechnology, the life sciences and chemistry. The Distillery goes beyond the abstracts to explain the commercial relevance of featured research, including licensing status and companies working in the field, where applicable.
This week in therapeutics includes important research findings on targets and compounds, grouped first by disease class and then alphabetically by indication.
This week in techniques includes findings about research tools, disease models and manufacturing processes that have the potential to enable or improve all stages of drug discovery and development.