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Product Development
Realities of limited manufacturing capacity for COVID-19 vaccines hit Horizon’s Tepezza launch

In a blow to what has been one of the more successful drug launches of the year, Operation Warp Speed has commandeered some of Horizon’s manufacturing slots for thyroid eye disease ...

Next-generation checkpoints acting on NK and T cells: Data Byte

Following the early success of anti-TIGIT mAbs in clinical development this year, interest in next-generation checkpoints has been on the rise, and there’s reason to believe that checkpoints ...

Emerging Company Profile
Vigil: restoring the vigilance of microglia

Incubated by Atlas Venture and led by former Ipsen CBO Ivana Magovčević-Liebisch, Vigil launched last week with $50 million in series A financing to advance two TREM2 agonists ...

Deals
GSK adds to next-generation checkpoint pipeline with Surface deal

GlaxoSmithKline’s $85 million deal with Surface Oncology caps off a big month for NK cell technologies and adds PVRIG to the growing list of NK cell checkpoint targets entering pharma ...

Novartis to build out neuropsychiatry pipeline via Cadent takeout

Cadent’s neuropsychiatry portfolio gives Novartis clinical programs in an area that the pharma has been eyeing for business development opportunities.  Novartis AG (NYSE:NVS; SIX:NOVN) ...

Dec. 17 Quick Takes: Ultragenyx gains rights to Mereo’s setrusumab; plus Verily’s $700M raise, dMed’s listing plans, Virios’ IPO   

Ultragenyx gains ex-Europe rights to Mereo’s setrusumabUltragenyx Pharmaceutical Inc. (NASDAQ:RARE) licensed ex-European rights to setrusumab from Mereo BioPharma Group plc (LSE:MPH; ...

Finance
New Italian VC’s first play is Spanish biotech chasing notoriously difficult target 

Recently launched European investment vehicle AurorA Science has placed its first marker on a company going after one of life sciences’ most infamous oncogene targets: MYC. AurorA Science ...

Management Tracks
Rim named CEO of Samsung Biologics as Sarepta unveils promotions; plus Coughlin, Iovance, SpringWorks and NodThera

Samsung Biologics promoted EVP John Rim to president and CEO. Before joining the South Korean company in 2018, Rim worked for Roche (SIX:ROG; OTCQX:RHHBY) and its Genentech Inc. unit for 14 years in ...

BioCentury ISSN 1097-7201