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Product Development
Finch’s microbiome therapy clears bar in pivotal C. diff readout

A pivotal Phase II readout for Finch’s microbiome treatment for recurrent Clostridium difficile infection paves the way for a Phase III trial that will further test the ...

T cell tests aim for broader picture of COVID-19 immunity

While the COVID-19 testing conversation has centered on assays for antiviral antibodies or the virus itself, at least two companies think T cell tests could catch patients the ...

Another blow for hydroxychloroquine, as Novartis stops COVID-19 study

Citing recruitment difficulties that render trial completion unfeasible, Novartis has discontinued its hydroxychloroquine study for COVID-19. The announcement is the latest in a ...

Daily Chart: COVID-19 vaccines by phase and modality

Among the 157 COVID-19 vaccines in development, at least 18 have reached the clinic.

Sichuan Clover Biopharmaceuticals Inc. is the latest company to enter ...

Regulation
FDA guidance aims to help sponsors salvage trials disrupted by COVID-19

As COVID-19 safety concerns and social distancing measures continue to disrupt clinical trials around the U.S., FDA has released

Politics, Policy & Law
House lawmakers call for transparency, independent review for COVID-19 vaccine program

A trio of Democrats on the House Oversight Committee are asking FDA for more information on how the agency plans to evaluate and deploy COVID-19 vaccines, in an effort to ensure ...

Finance
Forma, Repare shine in first-day performances as biotech IPOs on NASDAQ maintain momentum

Three of four life sciences IPOs priced above expectations ahead of Friday’s session, and two biotechs in the group -- Forma and Repare -- posted big gains in their first trading ...

Translation in Brief
CAR Ts against senescent cells; plus NIH program for ALS, sex-dependent COVID-19 immune responses and more

CAR T liver fibrosis therapy
Memorial Sloan Kettering Cancer Center researchers have generated CAR T cells against PLAUR, which is involved in ...

Management Tracks
Nurix bolsters leadership; plus Lynch named Xilio chairman, Edgewise, BioXCel, Catabasis, Catalyst and more

Nurix Therapeutics Inc. has announced a slew of leadership changes including Gwenn Hansen’s promotion to CSO from SVP of research, and Hans van Houte’s promotion ...

BioCentury ISSN 1097-7201