Deals

GSK adds to next-generation checkpoint pipeline with Surface deal

GlaxoSmithKline’s $85 million deal with Surface Oncology caps off a big month for NK cell technologies and adds PVRIG to the growing list of NK cell checkpoint targets entering pharma pipelines. ...

Novartis to build out neuropsychiatry pipeline via Cadent takeout

Cadent’s neuropsychiatry portfolio gives Novartis clinical programs in an area that the pharma has been eyeing for business development opportunities.  Novartis AG (NYSE:NVS; SIX:NOVN) will acquire Cadent Therapeutics Inc. for $210 million up front and...

Dec. 15 Quick Takes: Singlera raises $150M for cancer dx; plus AnGes-Emendo, Entresto, vTv and Unity

Cancer screening play Singlera raises megaroundSinglera Genomics Inc. raised $150 million in a series B round led by the CICC Kai Tak Innovative Biomedicine Fund, and co-led by Detong Capital and Furong Investment. Fellow new...

Third strike for Jyseleca takes therapy out of play in U.S. as focus of Gilead, Galapagos deal shifts to IPF

Four months after Jyseleca’s surprise setback at FDA, Gilead and Galapagos are abandoning U.S. development of the therapy that was once the centerpiece of a $5 billion deal between the companies.  ...

Prevail acquisition affords Lilly an ‘entry point’ in gene therapy, with more deals likely to follow

In Prevail, Lilly found an M&A target with expertise in one of its core areas — neuroscience — that can also be a building block around which it expects to amass a gene therapy pipeline via more...

Hillhouse’s Overland builds momentum with second marquee China deal with Allogene

Allogene has found its gateway to China via a deal with Hillhouse-backed Overland that gives the newly launched China company its second partner and an allogeneic CAR T cell platform. The news came...

In $39B deal, AZ looks to grow rare disease business while Alexion’s investors gain value recognition

AstraZeneca’s planned $39.4 billion takeout of Alexion gives the biotech’s shareholders an exit from a stock that’s largely been tracking sideways for years despite topline growth, and provides the pharma...

Ipsen is casting a wider BD net under new CEO Loew

With a pipeline heavy on line extensions and its bestseller headed toward a patent cliff, new Ipsen CEO David Loew is doubling down on the mid-cap biopharma’s commitment to external innovation. But...

Late in a year of cancer deals, Gilead spends $1B+ to add an antiviral for HDV

Near the end of a year when most of Gilead’s over $30 billion in deals were in cancer, the company’s latest billion-dollar acquisition showed an appetite for growth in its area of greatest historical strength:...

More enthusiasm for ADCs as Boehringer buys NBE, gaining conjugate platform

Weeks after Merck & Co.’s multibillion dollar takeout of VelosBio, Boehringer believes its purchase of NBE in a smaller deal will give it an earlier-stage, best-in-class product against the same target. Boehringer Ingelheim GmbH will acquire...

Dec. 7 Quick Takes: Sino pays $515M for Sinovac stake; plus BioCryst, Roivant, AbCellera, Syros, YZY, Maze

Sino Biopharm buys $515M stake in SinovacSino Biopharmaceutical Ltd. (HKEX:1177) paid $515 million for a 15% stake in Sinovac Biotech Ltd. (NASDAQ:SVA). The proceeds will fund development and production capacity expansion for Sinovac's Phase III-stage...

Adding first CAR T to growing cell therapy unit, Bayer picks Atara’s allogeneic program targeting mesothelin

Via a deal with Atara, Bayer’s latest additions to its new gene and cell therapy unit are an allogeneic CAR T treatment that the pharma hopes can treat solid tumors — and an autologous version that...

Artios picks Germany’s Merck for first major pharma collaboration in synthetic lethality

Artios’ deal with German pharma Merck represents the latest vote of confidence in the DNA damage repair sector, and extends the privately held biotech’s cash runway as it prepares for its first clinical trials. For its...

Viracta to start pivotal trial as public company following Sunesis merger, private placement

An investor syndicate is backing Viracta with $105 million in fresh capital as the biotech goes public via a reverse merger and plans a pivotal trial of its lead therapy targeting EBV-positive lymphomas. By merging...

With $1.5B Sage deal, Biogen bolsters Phase III pipeline ahead of aducanumab decision

Biogen is paying Sage $1.5 billion up front to gain rights to two late-stage CNS products, bolstering the company’s pipeline as it approaches one of the biggest binary decisions in recent industry...