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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) Casein kinase 1α (CSNK1A; CKI-α) Mouse and cell culture studies suggest …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) DNA (cytosine-5-)-methyltransferase 3a (DNMT3A) R882H In vitro studies …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Fas receptor (CD95) In vitro and mouse studies suggest blocking CD95 signaling could help …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer miR-BART9 In vitro and mouse studies suggest blocking Epstein-Barr virus (EBV) miR-BART9 could help …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Signal transducer and activator of transcription 3 (STAT3) In vitro and mouse studies identified a …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Tubulin In vitro and human studies suggest paclitaxel induces cell death by promoting the formation …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cervical cancer PC4 and SFRS1-interacting protein (PSIP1; LEDGF; p75; LEDGF/p75) Studies in cell culture and…

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Ovarian cancer Ras-related associated with diabetes (RRAD) Human sample, cell culture and mouse studies …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Cardiovascular disease Transmembrane 6 superfamily member 2 (TM6SF2) Studies in human …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Dental disease Periodontitis IL-17A; IL-23 Patient and mouse studies suggest inhibiting IL-17A or IL-23 could help…

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Asthma Potassium channel Kv1.3 (KCNA3) Rat studies suggest KCNA3 antagonists could be useful for …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) RE1-silencing transcription factor (REST; NRSF) Studies in human samples and …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD); frontal temporal dementia (FTD) Microtubule-associated protein-t (MAPT; tau; …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Autoimmune disease; inflammation Platelet/endothelial cell adhesion molecule 1 (PECAM1; CD31) In vitro and …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Autoimmune disease; inflammation Tumor necrosis factor-a (TNF-a) Mouse and in vitro culture studies …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Stroke; ischemia/reperfusion injury IL-21 Mouse studies suggest inhibiting IL-21 signaling could help …

    Published on 4/17/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Epithelial membrane protein 2 (EMP2) Patient sample and mouse studies suggest targeting EMP2 …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Anoctamin 1 calcium activated chloride channel (ANO1) In vitro studies suggest compounds that promote…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) Not applicable In vitro and mouse studies suggest the rheumatoid …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Colorectal cancer Splice variant v6 of CD44 (CD44v6); phosphoinositide 3-kinase (PI3K) In vitro and mouse …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lymphoma Jagged 1 (JAG1); notch 2 (NOTCH2); fibroblast growth factor 4 (FGF4); fibroblast growth factor …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Non-small cell lung cancer (NSCLC); bone cancer Ubiquitin specific peptidase 1 (USP1); WD repeat domain 48 (…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Sterol O-aceyltransferase 1 (SOAT1; ACAT1) Studies in patient samples, mice and cell culture…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Atherosclerosis Peroxisome proliferation-activated receptor-g (PPARG; PPARg); myeloid-…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Blood clots; thrombosis Thrombin (factor IIa; F2) In vitro studies suggest an allosteric …

    Published on 4/10/2014

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