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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Epithelial membrane protein 2 (EMP2) Patient sample and mouse studies suggest targeting EMP2 …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Anoctamin 1 calcium activated chloride channel (ANO1) In vitro studies suggest compounds that promote…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) Not applicable In vitro and mouse studies suggest the rheumatoid …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Colorectal cancer Splice variant v6 of CD44 (CD44v6); phosphoinositide 3-kinase (PI3K) In vitro and mouse …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lymphoma Jagged 1 (JAG1); notch 2 (NOTCH2); fibroblast growth factor 4 (FGF4); fibroblast growth factor …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Non-small cell lung cancer (NSCLC); bone cancer Ubiquitin specific peptidase 1 (USP1); WD repeat domain 48 (…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Sterol O-aceyltransferase 1 (SOAT1; ACAT1) Studies in patient samples, mice and cell culture…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Atherosclerosis Peroxisome proliferation-activated receptor-g (PPARG; PPARg); myeloid-…

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Blood clots; thrombosis Thrombin (factor IIa; F2) In vitro studies suggest an allosteric …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Farnesoid X receptor (FXR; NR1H4) Mouse studies suggest FXR is required to …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Cirrhosis Synoviolin (SYVN1; HRD1) Studies in human samples and mice suggest inhibiting HRD1 could …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Pannexin 1 (PANX1) In vitro studies suggest avoiding PANX1 inhibition could …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Peroxisome proliferation-activated receptor-g (PPARG; PPARg) Studies in mice and human …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Meningitis; pneumonia Properdin Mouse studies suggest recombinant properdin could help protect …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation Leukotriene A4 hydrolase (LTA4H) Structure-based design studies led to an LTA4H inhibitor…

    Published on 4/10/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphocytic leukemia (ALL) Deoxycytidine kinase (DCK) In vitro and mouse …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute promyelocytic leukemia (APL) Retinoic acid receptor-α (RARA); promyelocytic …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Mitogen-activated protein kinase kinase 4 (MAP2K4; MKK4) Cell …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer G protein-coupled receptor 161 (GPR161) Patient sample and cell …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Cannabinoid CB2 receptor (CNR2) In vitro and mouse studies suggest a CNR2-…

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Heat shock protein 90 (Hsp90) In vitro and mouse studies suggest a new …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer IL-23; CD40 Mouse studies suggest combination therapy with IL-23 and CD40 …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma; prostate cancer; colon cancer CTLA-4 (CD152) Mouse studies suggest …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Ubiquitin specific peptidase 9 X-linked (USP9X; FAF); v-ets …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Coronary artery bypass graft (CABG) surgery Transforming growth …

    Published on 4/3/2014

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