BioCentury

7:00 AM GMT, Oct 17, 2011
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Emerging Company Profile

KalVista: Filling the VEGF void

KalVista Pharmaceuticals Ltd. believes its small molecule plasma kallikrein inhibitors will treat diabetic macular edema on par with VEGF inhibitors and will work in more patients. The biotech also hopes to offer injectable and oral delivery options for clinicians.

Diabetic macular edema (DME) is caused by increased permeability of the retinal vasculature, which results in fluid accumulation in the macula and ultimately vision loss.

First-line therapy includes laser-induced retinal photocoagulation, which can slow or reverse disease progression and reduce

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This article and the information contained in BioCentury's publications and services are solely for your own personal, non-transferable licensed use and cannot be shared with any other individuals. For information about adding subscribers to your account or obtaining article reprints, please contact support@biocentury.com.