Poring over DNA

"Lockable" DNA channels control compound release by lipid nanoparticles

Researchers at University College London (UCL) have built "lockable" DNA nanopores that control the release of molecular cargo from vesicles using oligonucleotide "keys". The team thinks the straightforward design principles and low cost of DNA channel engineering could enable widespread use of the technology, including therapeutic applications such as the targeted release of toxic chemotherapeutics.


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