ARTICLE | Translation in Brief
In silico prescription
How an in silico model could help prescribe cancer therapies
April 23, 2015 7:00 AM UTC
A new in silico model matches driver mutations with drug mechanisms and shows current guidelines miss a lot of possible treatments.
Anin silico model from researchers in Barcelona that matches cancer mutations to drug mechanisms suggests only about 6% of tumors can benefit from approved drugs recommended by clinical guidelines. On the other hand, about 40% of tumors could be treated by drugs marketed for other cancers, while about 73% of tumors could respond to treatments in development...