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In silico prescription

How an in silico model could help prescribe cancer therapies

April 23, 2015 7:00 AM UTC

A new in silico model matches driver mutations with drug mechanisms and shows current guidelines miss a lot of possible treatments.

Anin silico model from researchers in Barcelona that matches cancer mutations to drug mechanisms suggests only about 6% of tumors can benefit from approved drugs recommended by clinical guidelines. On the other hand, about 40% of tumors could be treated by drugs marketed for other cancers, while about 73% of tumors could respond to treatments in development...