ARTICLE | Targets & Mechanisms
Nanoparticles for the flu
June 6, 2013 7:00 AM UTC
An NIH team has created a self-assembling influenza nanoparticle that induces the production of antibodies against a wider range of flu strains than traditional vaccines.1 The team hopes to test the immunogenicity of the vaccine in humans once a GMP manufacturing process is developed.
The nanoparticle consists of a fusion of the influenza A virus hemagglutinin (HA) from New Caledonia H1N1 1999 strain and ferritin, an iron-storage protein from Helicobacter pylori...