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  • Pfizer moves up

    How Pfizer, Merck KGaA plan to catch up in cancer immunotherapy

    Pfizer and Merck KGaA hope their deal will make them front-runners in cancer immunotherapy combos, but they'll have to catch Merck & Co.

    Published on 11/24/2014
  • Figure: Combo catch-up

    Pfizer moves up Combo catch-up Pfizer Inc. (NYSE:PFE) and Merck KGaA (Xetra:MRK) hope to race to the front in cancer immunotherapy with combination studies of Merck's PD-L1 inhibitor MSB0010718C, which is in Phase …

    Published on 11/24/2014
  • Poste a pourvoir

    Board mandates mean shoring up Lantus losses won't be easy for Sanofi CEO

    Sanofi's new CEO will have a hard row to hoe to offset Lantus declines, as the board has taken easy solutions off the table.

    Published on 11/17/2014
  • Figure: Pipeline by source

    Poste à pourvoir Pipeline by source During his tenure as CEO of Sanofi (Euronext:SAN; NYSE:SNY), Chris Viehbacher and President of Global R&D Elias Zerhouni pruned the pharma's pipeline of uncompetitive programs and…

    Published on 11/17/2014
  • Figure: Sanofi share performance

    Poste à pourvoir Sanofi share performance Shares of Sanofi (Euronext:SAN; NYSE:SNY) have gained 129% since Chris Viehbacher became CEO, after adjusting for dividends. This compares to a 205% gain for an equal price-…

    Published on 11/17/2014
  • Table: Filling in for Lantus

    Poste à pourvoir Filling in for Lantus The six drugs Sanofi (Euronext:SAN; NYSE:SNY) plans to launch in 2015-16 could make up for part of the recent and unexpected shortfall in Lantus insulin glargine sales, but …

    Published on 11/17/2014
  • Table: Sanofi comps

    Poste à pourvoir Sanofi comps During former CEO Chris Viehbacher's tenure at Sanofi (Euronext:SAN; NYSE:SNY), which began in December 2008, the pharma lagged most of its peers in EPS growth. EPS has posted an …

    Published on 11/17/2014
  • Lantus limbo

    What Sanofi's Lantus rebates mean for new insulin candidates launching in 2015

    Lantus rebates could spell reimbursement pressure for new insulin products Sanofi and others will be launching in 2015 and 2016.

    Published on 11/17/2014
  • Translation in Asia

    How J&J's new Asia Pacific Innovation Center in Shanghai will access innovation

    J&J's new Asia Pacific Innovation Center will initially do more translation of academic work than the other three centers.

    Published on 11/3/2014
  • Figure: Deals by center

    Translation in Asia Deals by center The new Asia Pacific Innovation Center in Shanghai is the fourth and final in a two-year-old initiative aimed at increasing the number and speed of early stage deals by Johnson & …

    Published on 11/3/2014
  • Figure: Innovation by segment

    Translation in Asia Innovation by segment Dong Wu, head of Johnson & Johnson's (NYSE:JNJ) new Asia Pacific Innovation Center, comes from the consumer products division, which should help all four centers with …

    Published on 11/3/2014
  • Box: Other gripes

    Amgen on notice Other gripes Among activist investor Third Point LLC's gripes with Amgen Inc. are the biotech's SG&A spending and its 2013 acquisition of Onyx Pharmaceuticals Inc. Third Point noted that Amgen …

    Published on 10/27/2014
  • Figure: Amgen R&D Comps

    Amgen on notice Amgen R&D comps Over the past 10 years, Amgen Inc. (NASDAQ:AMGN) has spent $29.3 billion on R&D - 1.6x the combined spending by Biogen Idec Inc. (NASDAQ:BIIB) and Gilead Sciences Inc. (NASDAQ:GILD)…

    Published on 10/27/2014
  • Figure: Amgen SG&A comps

    Amgen on notice Amgen SG&A comps Amgen Inc. (NASDAQ:AMGN) has spent $37.4 billion on SG&A over the past 10 years, or 25% of its revenues. This compares to $9.4 billion (23%), for Biogen Idec Inc. (NASDAQ:BIIB) and $…

    Published on 10/27/2014
  • Amgen on notice

    How splitting up doesn't address Amgen's struggles creating value-driving assets

    Third Point says splitting Amgen will unleash value, but the portfolio shows the biotech is hard pressed to advance value-driving assets.

    Published on 10/27/2014
  • Guest Commentary: Miracle or good medicine?

    Peter Reikes' experience reminds us how much patients depend on innovation

    Amidst the rancorous debate over healthcare, Peter Reikes' experience reminds us what really happens to patients, and how much they depend on medical innovation.

    Published on 10/27/2014
  • Guest Commentary: Paying for cures

    How payers, companies can evaluate the value of new drugs

    A Guest Commentary proposes a framework to help evaluate the value of drugs and define financing options to ensure access.

    Published on 10/20/2014
  • Table: Avalere's five Ps

    Paying for cures Avalere's five Ps The Five Ps tie the clinical facets of new innovations to how they may impact specific payer markets in the U.S. to identify specific solutions that balance patient access with …

    Published on 10/20/2014
  • Box: Pruned by setbacks

    Streamlining Takeda's Profit Story Pruned by setbacks Takeda Pharmaceutical Co. Ltd. has experienced several recent setbacks for late-stage compounds and new launches. In December 2013, the company discontinued …

    Published on 10/13/2014
  • Box: Streamlining operations

    Streamlining Takeda's Profit Story Streamlining operations Takeda Pharmaceutical Co. Ltd. said the goal of the commercial and R&D reorganization announced last month is to make its operations more agile and to allow…

    Published on 10/13/2014
  • Figure: Takeda chronicles

    Streamlining Takeda's Profit Story Takeda chronicles Shares of Takeda Pharmaceutical Co. Ltd. (Tokyo:4502) have fallen 45% from a peak of ¥8,400 in February 2007 to ¥4,587 last Friday. The decline started when …

    Published on 10/13/2014
  • Figure: The bottom line

    Streamlining Takeda's Profit Story The bottom line While revenues for Takeda Pharmaceutical Co. Ltd. (Tokyo: 4502) have increased by 4% a year since the financial crisis in 2008-09, the pharma's EPS has declined an …

    Published on 10/13/2014
  • Table: Takeda comps

    Streamlining Takeda's Profit Story Takeda comps Takeda Pharmaceutical Co. Ltd. (Tokyo:4502) has reported steady cost increases on an absolute basis and as a percentage of revenues since FY04, just before starting a …

    Published on 10/13/2014
  • Streamlining Takeda's Profit Story

    Takeda needs to execute on cost-cutting, pipeline to meet EPS expectations

    After a decade of acquisitions, Takeda is focused on getting costs in line with global peers and meeting expectations for EPS expansion.

    Published on 10/13/2014
  • Guest Commentary: Price cuts in HCV

    Guest Commentary: Why HCV therapy costs could start dropping fast

    A Guest Commentary predicts HCV prices will fall, and that the forces driving economic change in HCV will do so in other categories.

    Published on 10/6/2014

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