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Chronological Index of : Strategy

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  • Weighing in on obesity

    How Contrave and liraglutide could succeed in obesity

    The newest obesity drugs will have the weight of pharma companies behind them in the key cardiometabolic markets required for success.

    Published on 9/22/2014
  • Table: Obesity Runway

    Weighing in on obesity Obesity runway If Orexigen Therapeutics Inc. (NASDAQ:OREX), Takeda Pharmaceutical Co. Ltd. (Tokyo:4502) and Novo Nordisk A/S (CSE:NVO; NYSE:NVO) are successful in building physician awareness …

    Published on 9/22/2014
  • Cost and quality: Box: CMS bundles up

    Cancer: Cost and quality CMS bundles up CMS has signaled an interest in a bundled model for cancer reimbursement that would include physician services plus infused and outpatient drugs. The Medicare agency would not…

    Published on 9/15/2014
  • Cost and quality: Box: WellPoint's pathway

    Cancer: Cost and quality WellPoint's pathway WellPoint Inc. is piloting a treatment pathways program that dictates what drugs should be used based on tumor type and stage of disease. Clinicians who follow the …

    Published on 9/15/2014
  • Cancer: Cost and quality

    How cancer reimbursement reform could boost or inhibit drug use

    Payer reforms of cancer care may result in more drug use, depending on how the schemes balance cost-effectiveness and quality outcomes.

    Published on 9/15/2014
  • PI(3)King AbbVie

    How AbbVie, Infinity plan to make the most of duvelisib's best-in-class potential

    In one of the biggest recent cancer licensing deals, Infinity picks AbbVie to carve out a niche for duvelisib in hematologic cancers.

    Published on 9/8/2014
  • Parsing Roche's IPF bet

    How Roche can use mortality data, new indications to create Esbriet blockbuster

    Roche's ROI on Esbriet hinges on mortality data to improve uptake and reimbursement, pricing power in the U.S. and label expansions.

    Published on 9/8/2014
  • Table: On deck in IPF

    Parsing Roche's IPF bet On deck in IPF At least 16 compounds are in clinical development to treat idiopathic pulmonary fibrosis (IPF), with at least eight in Phase II testing. As the Phase III trials for both …

    Published on 9/8/2014
  • Table: Big upfronts

    PI(3)King AbbVie Big upfronts Since 2009, at least six licensing deals for clinical-stage cancer programs had upfront payments of $100 million or more. The $275 million up front in last week's deal between Infinity …

    Published on 9/8/2014
  • Back to School Issue: Paying the piper

    22nd BioCentury Back to School Issue: Time to try new pricing schemes

    As the drumbeat for cost-based pricing grows louder, the 22nd Back to School essay says industry must experiment with new pricing models in which the cost of a given treatment is based on the patient-defined value of …

    Published on 9/1/2014
  • Box: Best price barrier

    Paying the piper Best price barrier The Medicaid best price rule for outpatient drugs is cited as a barrier to implementing new pricing models in the U.S. Companies that want an outpatient drug to be covered by …

    Published on 9/1/2014
  • Box: Big(ger) in Japan

    Paying the piper Big(ger) in Japan Drug prices in Japan are subject to mandatory reductions after launch, but there is an opportunity for companies to receive a premium, as well as for the price to be increased …

    Published on 9/1/2014
  • Box: Capping Orphans

    Paying the piper Capping Orphans Academics at Duke University have proposed a "grant-and-access" model for ultra-Orphan drugs based on the premise that high R&D costs are limiting investment in these rarest of …

    Published on 9/1/2014
  • Box: Code conundrum

    Paying the piper Code conundrum The U.S. drug coding system presents a challenge for companies that want to try flat pricing schemes. Once a drug is approved in the U.S., CMS establishes a code that connects the …

    Published on 9/1/2014
  • Box: Financing cures

    Paying the piper Financing cures Tanisha Carino of Avalere Health LLC and Scott Gottlieb of the American Enterprise Institute (AEI) both acknowledge that current pricing and reimbursement models are not structured …

    Published on 9/1/2014
  • Box: Pricing Cerdelga

    Paying the piper Pricing Cerdelga Finding U.S. Medicaid pricing regulations too limiting for a bolder experiment just yet, Genzyme Corp. is adopting a version of portfolio pricing lite for two Gaucher's drugs with …

    Published on 9/1/2014
  • Box: Sovaldi nightmares

    Paying the piper Sovaldi nightmares The great Sovaldi debate often overlooks that sofosbuvir is not so much more expensive than the previous standard of care. In interferon-containing regimens for treatment-naïve …

    Published on 9/1/2014
  • Box: Waiting for Kalydeco

    Paying the piper Waiting for Kalydeco Australian health authorities have proposed a pay-for-performance deal for Vertex Pharmaceuticals Inc.'s Kalydeco ivacaftor that would set per-patient reimbursement based on …

    Published on 9/1/2014
  • Figure: Out of room

    Paying the piper Out of room According to IMS Health Holdings Inc., worldwide drug expenditures are climbing out of the patent trough, suggesting that any "room" created by patent expirations was ephemeral.

    Published on 9/1/2014
  • Figure: Uphill climb

    Paying the piper Uphill climb In the U.S., average wholesale price (AWP) often goes up even as competitors enter the market. The data below show price increases across five highly competitive categories. Three are …

    Published on 9/1/2014
  • Table: Fast, not cheap

    Paying the piper Fast, not cheap Drug company efforts to improve R&D success rates by developing targeted drugs, plus the combined efforts of industry and regulators to truncate development and approval pathways, …

    Published on 9/1/2014
  • Breathing room

    Almirall COPD assets give AZ time for respiratory pipeline to mature

    AstraZeneca's acquisition of Almirall's respiratory assets should buy time until other compounds in the pharma's pipeline mature.

    Published on 8/18/2014
  • Figure: Respiratory sales

    Breathing room Respiratory sales AstraZeneca plc (LSE:AZN; NYSE:AZN) expects to almost double respiratory revenues to about $8 billion by 2023. However, the company is still well behind GlaxoSmithKline plc (LSE:GSK;…

    Published on 8/18/2014
  • Table: AZ-Almirall respiratory pipeline

    Breathing room AZ-Almirall respiratory pipeline Although its deal with Almirall S.A. (Madrid:ALM) doesn't give AstraZeneca plc (LSE:AZN; NYSE:AZN) any clinical assets with mechanisms of action it doesn't already …

    Published on 8/18/2014
  • Table: Deeply Novel

    Breathing room Deeply novel AstraZeneca plc (LSE:AZN; NYSE:AZN) appears to have more clinical compounds targeting a wider range of novel targets/mechanisms of action for asthma and chronic obstructive pulmonary …

    Published on 8/18/2014

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