Inflection: Pairing up PIM

Inflection combines pan-PIM kinase, PI3K, mTOR inhibitors in single molecule

Inflection Biosciences Ltd. is developing pan-PIM kinase inhibitors that are a few years behind large pharma competitors, but the biotech's compounds can be structurally linked to other kinase inhibitors for cancer. The small molecules thus could address multiple pathways with a single compound, simplifying combination therapy.

PIM kinases are a family of serine threonine kinases involved in cell cycle regulation, apoptosis,

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