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EnBiotix using two mechanisms to increase sensitivity to antibiotics
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EnBiotix: Enhancing antibiotics
Monday, February 11, 2013
Inc. is discovering compounds that make infections more susceptible to
existing antibiotics either by increasing the bacterias' production of reactive
oxygen species, or by activating their metabolic pathways. The company is
aiming for a discovery alliance followed by an A round that will help fund
development of its candidates.
EnBiotix's discovery programs are based on the work of Boston
University's James Collins, whose lab has used systems biology
approaches to study bacterial responses to antibiotics. Collins is a professor
of biomedical engineering at the university, a founding core member of the Wyss
Institute for Biologically Inspired Engineering at Harvard University
and a Howard
Hughes Medical Institute investigator.
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