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19177 items
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

TSIN rethinks its ambitions

TSI Corp., suffering indigestion from an ambitious growth-oriented strategy, last week embarked on a downsizing that it hopes will be in place by the end of the year. James Sherblom resigned as chairman, president and...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

CentoRX cost-benefit comparison

CentoRX cost-benefit comparison Trial Implied Implied Trial Implied Implied Cost incidence: number in cost to incidence: number in cost to Event to treat placebo total pop. treat CentoRx total pop. treat CABG $15,000 3.60%...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

Anticoagulant crowd feels squeeze

Anticoagulant crowd feels squeeze In this era of cost-consciousness, clinical efficacy may not be enough to convince hospitals and doctors to use new products, particularly in crowded fields such as anticoagulants for acute...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

non-cardiac surgery

Untapped market: non-cardiac surgery Dennis Mangano, a professor of anesthesiology at the University of California in San Francisco, suggests that a big growth area for cardiovascular drugs will be use in non-cardiac surgery. About 25 million...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

Stay or go?

MicroGeneSys quandary: Stay or go? WASHINGTON - MicroGeneSys Inc., no longer the exclusive beneficiary of a $20 million appropriation to test its AIDS vaccine and unhappy with the probable conditions of an NIH-run comparison trial of...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

TSIN

TSIN...
12:00 AM, Apr 19, 1993  |  BioCentury | Politics, Policy & Law

Genentech switches on biodiversity pact

Genentech Inc. said it has joined a business-environmental coalition that is urging the Clinton administration to sign the Convention on Biodiversity that was rejected by the Bush Administration in part on urging from biotech companies...
12:00 AM, Apr 19, 1993  |  BioCentury | Tools & Techniques

GM-CSF as immunostimulant

GM-CSF as immunostimulant Somatix Therapy Corp. said that in mouse studies GM-CSF genes inserted into inactivated melanoma cells conferred systemic immunity for at least two months in 80 percent of animals challenged with live...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

MAbs could alter PDLI core program

Protein Design Labs Inc. acquired from Sandoz Pharma Ltd. and Sandoz Pharmaceuticals Corp. two human antiviral monoclonal antibodies that will become its lead clinical candidates, as well as the technology to produce them. That technology...
12:00 AM, Apr 19, 1993  |  BioCentury | Strategy

Glut of competition

Glut of competition Glut of competition Thrombin inhibitors or thrombin synthesis inhibitors ProductCompanyIndicationStatusHirulogBiogenUnstable anginaPhase IIIAngioplastyPhase III to startAdjunct to streptokinase in acute MI2d Phase II to startHirudinCiba-GeigyAngioplastyPhase IIIUnstable anginaPhase III to startWith tPA in MIPhase II...

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