BioCentury's websites will be down for upgrades starting at 9 p.m. PDT on Monday, August 26. We expect the downtime to last no more than 6 hours, and we apologize for any inconvenience.

12:00 AM
 | 
Dec 11, 2006
 |  BioCentury  |  Tools & Techniques

A new pain killer

It may be hard to believe that an endogenous painkiller more potent than morphine could go undiscovered, but it's true, according to a recent report in the Proceedings of the National Academy of Sciences.

In preclinical testing, opiorphan, a newly discovered short neuropeptide, was more potent than morphine and did not cause the same GI side effects. Opiorphan also may have potential applications in depression and anxiety.

The five-amino-acid peptide is expressed at very low levels in only certain areas of the brain. "It's not easy to isolate such a...

Read the full 439 word article

User Sign in

Trial Subscription

Get a 4-week free trial subscription to BioCentury

Article Purchase

$150 USD
More Info >