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12:00 AM
 | 
Jun 02, 2003
 |  BioCentury  |  Tools & Techniques

Replicating human glycosylation

Although fungal systems are less costly and more efficient at producing proteins than mammalian systems, they fail to recreate the complex human glycosylations that are often necessary for the biological activity of protein therapeutics. Enter GlycoFi Inc., which has been able to engineer yeast and other fungal expression systems to perform complex human-like glycosylation.

The company recently announced its first deal for the technology, which incorporates the machinery necessary to replicate human N-linked glycosylation structures in yeast and other fungi. GlycoFi (Lebanon, N.H.) will use its yeast and filamentous fungi-based manufacturing technology to manufacture an undisclosed protein therapeutic from...

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