BioCentury
ARTICLE | Tools & Techniques

Fast genetic linkage mapping

May 6, 2002 7:00 AM UTC

Mapping complex genetic traits usually needs typing of polymorphic markers in a huge number of individuals. Epigenomics AG now has in-licensed a technology that it believes is suited to quickly map affected-relative pairs and does not require conventional polymorphic markers or gel electrophoresis.

The ILD (Identification of Linkage Disequilibrium) technology uses principles similar to those used in Genomic Mismatch Scanning (GMS), which was described for yeast in 1993.However, many research groups had difficulty transferring GMS to human genetics...