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12:00 AM
May 07, 2001
 |  BioCentury  |  Tools & Techniques

Managing cancer drug metabolism & excretion

Managing cancer drug metabolism & excretion

Tumor resistance to chemotherapy often develops over time, forcing clinicians to change the treatment protocol. Now researchers from the City of Hope National Research Center (Duarte, Calif.) have published mechanisms of chemoresistance associated with drug-induced activation of SXR, a nuclear hormone receptor. The findings, published last week in Nature Medicine,could provide a basis for...

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