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 | 
Mar 26, 2001
 |  BioCentury  |  Tools & Techniques

Enzybiotics: Phaging back in

So, naturalists observe, a flea

Has smaller fleas that on him prey;

And these have smaller still to bite 'em;

And so proceed ad infinitum

- Jonathan Swift

The problem of increasing bacterial resistance to antibiotics has companies searching for new antibiotics. New Horizons Diagnositics Corp. has come up with an elegant method of treating and preventing bacterial infections using nature's own pest management: bacterial pathogens called bacteriophages that reproduce in and kill bacteria.

This approach had been tried in the 1930s but

phage were not found to be reliable. And with the advent of sulfa drugs and antibiotics, phages fell out of favor. New Horizon's twist is to use the phage's bacteriolytic enzymes to destroy bacteria,...

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