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12:00 AM
Jan 23, 2006
 |  BioCentury  |  Strategy

Protein space race continues

Two recent deals by Ablynx N.V. illustrate the ongoing rush by big pharma companies to make sure they are players in the next-generation antibody/protein space.

In the past two weeks, Ablynx has signed deals covering therapeutic applications of its Nanobody platform with Novartis AG (NVS; SWX:NOVN, Basel, Switzerland) and Centocor Research & Development Inc. (Malvern, Penn.), a subsidiary of Johnson & Johnson (JNJ, New Brunswick, N.J.) (see B2 & BioCentury, Jan. 16).Nanobodies are single-domain antibody fragments derived from camelid antibodies that lack a light chain - a property that confers potentially significant advantages over both conventional antibodies and their fragments. These include high stability under conditions of high heat, high pH and the presence of enzymes; the potential for...

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