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12:00 AM
 | 
Jul 12, 2004
 |  BioCentury  |  Strategy

Two ends against the middle

Although Chiron Corp.'s acquisition of Sagres Discovery Inc. doesn't remedy its thin clinical pipeline in cancer, CHIR thinks the deal lays the foundation for a renewable internal source of oncology compounds. In addition, Sagres' approach to target discovery is opposite that of CHIR and other companies that use expression data to infer whether a gene may be a good target.

Sagres' high throughput Oncogenome technology uses a retrovirus that integrates randomly into a genome and up-regulates genes in mice. The genes that cause cancer are then cloned and Sagres uses the Celera...

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