BioCentury
ARTICLE | Product Development

Acacia's upside bonus

Acacia data show APD421 may be more effective than droperidol for PONV

June 18, 2012 7:00 AM UTC

Acacia Pharma Ltd. was searching for a safer version of droperidol, which is efficacious in preventing postoperative nausea and vomiting but not often used due to safety issues. Now Phase II data show APD421 actually may be more efficacious as well as safer.

Anesthesiologists have multiple options for preventing and treating postoperative nausea and vomiting (PONV), including dopamine receptor antagonists such as droperidol and serotonin (5-HT3) receptor antagonists such as ondansetron...