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12:00 AM
 | 
Dec 19, 2005
 |  BioCentury  |  Product Development

Taking the oil out

Both products inhibit lipase and thus prevent breakdown of fat into triglycerides. But something about cetilistat is different. In the gut, Xenical causes undigested fat to aggregate in small droplets that unite to form large oily spots. But for unknown reasons, cetilistat does not cause the droplets to unite.

"We don't know about the mechanism in detail," CEO Richard Palmer said. "But based on what we observe, patients don't have that much oily stool."

Whatever the mechanism, the data...

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