BioCentury
ARTICLE | Emerging Company Profile

Not PGE2's first Rodeo

How Rodeo's HPGD inhibitor could promote tissue regeneration

September 13, 2017 9:20 PM UTC

Rodeo Therapeutics Corp. is boosting prostaglandin E2 production within cells rather than delivering it systemically to promote tissue regeneration without the side effects that have dogged the molecule in the past.

Tissues up-regulate prostaglandin E2 (PGE2) in response to stress or injury to induce proliferation of the local stem cells that can repair them. ...