BioCentury
ARTICLE | Emerging Company Profile

Mining ALS possibilities

Patient-founded Treeway seeks to turn ALS into a manageable, chronic condition

January 25, 2016 8:00 AM UTC

Treeway B.V. was co-founded by two amyotrophic lateral sclerosis patients to develop a series of therapies that over time could turn the degenerative disease into a chronic, manageable condition. In the near term, the company is reformulating a marketed IV drug to improve efficacy as well as convenience for ALS patients.

In the longer term, the company hopes to translate the findings of a patient-driven European sequencing initiative into new treatments that can delay progression for much longer periods of time. Treeway co-founders CBO Bernard Muller and CFO Robbert Jan Stuit - who both have ALS - also helped found Project MinE, a European sequencing initiative headed by University Medical Center Utrecht researchers to find targetable genes and pathways in ALS...