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ARTICLE | Emerging Company Profile

Maximizing immunogenicity

Why OncoQR thinks its S-TIR vaccine can work better than other cancer vaccines

June 15, 2015 7:00 AM UTC

OncoQR ML is developing allogeneic cancer vaccines that use S-TIR active immunotherapy technology to increase immunogenicity compared with earlier approaches.

According to co-founder, Managing Director and COO Christof Langer, the company's "warhead" approach enables a much more potent immune response to S-TIR vaccines than other allogeneic cancer vaccines, which use a variety of immune stimulators including toll-like receptor 9 (TLR9) agonists. The warhead consists of a peptide with moieties targeting both TLR9 and Fc gamma receptor II (FCGRA2; CD32), and is linked to an antigen. ...