12:00 AM
Feb 03, 2014
 |  BioCentury  |  Emerging Company Profile

2bind: Results within minutes

2bind offers fast molecular interaction analysis using NanoTemper MST system

2bind GmbH has built a service business around microscale thermophoresis technology developed by partner NanoTemper Technologies GmbH. 2bind uses its in-house MST-compatible assays and NanoTemper's MST systems to analyze molecular interactions with quicker turnaround, greater flexibility and lower cost than comparable analyses using traditional technologies such as surface plasmon resonance.

Microscale thermophoresis technology (MST) assesses changes in a molecule's response to a temperature gradient to reveal information about molecular binding interactions and modifications. A molecule's response to a temperature gradient, called thermophoresis, is affected by parameters such as its size, charge and hydration shell. These parameters typically change when a molecule is bound or modified.

MST thus enables quantitative analysis of molecular interactions in solution by assessing how molecules respond to the force generated by a microscopic temperature gradient.


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