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12:00 AM
 | 
Oct 29, 2012
 |  BioCentury  |  Emerging Company Profile

PathoQuest: Positive identification

PathoQuest aims for rapid, detailed pathogen identification in transplant

Diagnostics for infection can take days to weeks to produce results and often serve only to rule out a given pathogen, without providing a positive diagnosis. PathoQuest S.A.S. is developing a sequencing-based diagnostic designed to identify the specific viral, bacterial or fungal culprit within 24 hours.

Today's diagnostics use culturing or PCR-based sequencing. The former tests can detect a specific bacterial or fungal infection but take up to two weeks for results.

PCR-based tests can detect a broader range of infections with results in 24-48 hours, but they require a priori knowledge of what pathogens might be present and thus can detect only a predefined set of organisms.

For either type of test, a negative result means the pathogen remains unknown, usually forcing doctors to treat the patient with a barrage of antibiotics instead of a more personalized regimen.

PathoQuest says its test can identify any pathogen in a blood sample within 24 hours and allow doctors to select a...

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