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ARTICLE | Emerging Company Profile

Ember Therapeutics: Burning obesity

Ember taking two-pronged approach to fat, insulin in obesity, diabetes

February 27, 2012 8:00 AM UTC

Ember Therapeutics Inc. is taking two therapeutic approaches to obesity and diabetes, one that is based on novel biology and another it thinks will improve on marketed PPAR gamma agonists. The company hopes to advance a lead candidate for each program into the clinic by 2014.

The company's primary focus is brown fat biology, according to President and Interim CEO Lou Tartaglia. Brown fat burns calories to generate heat and was long known to exist in rodents and human infants, but it wasn't until 2009 that brown fat was discovered in adults...