VCN: Anti-tumor Ad-vantages
VCN Biosciences' oncolytic virus penetrates tumor stroma to treat pancreatic cancer
Pancreatic cancer is highly resistant to drugs because about 80% of the tumor is stroma - normal fibrous and connective tissues that support cancer cell growth and invasion - that compounds cannot penetrate efficiently. To overcome this problem, VCN Biosciences S.L. is developing VCN-01, a genetically engineered adenovirus that selectively penetrates the tumor stroma and replicates in pancreatic tumor cells to kill them.
Pancreatic cancer is a large unmet medical need, with a five-year survival rate of less than 5%, according to the American Association for Cancer