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May 25, 2009
 |  BioCentury  |  Emerging Company Profile

Affomix: Whole proteome arrays

Antibody arrays are a more accurate tool for measuring protein levels in biological samples than commonly used mRNA-based methods. But the cost and time needed to generate antibodies has limited the space that can be covered to a few protein families.

Affomix Corp. has developed an automated yeast hybrid antibody screening technology that it believes will cut time and cost enough to develop a whole proteome antibody array.

"What we want to do is generate a proteome multiplex array," President Michael Sherman told BioCentury. "We want the scientists to be able to take a biological sample of any type, whether it's serum or a tumor sample, and be able to use our array to get an indication of the level of all the proteins in that sample."

According to Sherman, arrays that measure mRNA expression in biological samples are useful in most cases for detecting the presence of...

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