12:00 AM
 | 
Mar 19, 2007
 |  BioCentury  |  Emerging Company Profile

Genomic Vision: Combing stretched DNA

Identifying the genetic basis of disease is only partially addressed by SNP genotyping technologies. Genomic Vision S.A. has developed a complementary technology, dubbed Molecular Combing, that can visualize multiple whole genomes and quantitatively identify DNA substitutions of 1,000 or more bases.

According to Aaron Bensimon, co-founder, chairman and CEO, "more and more data is surfacing showing that polymorphisms are caused by larger permutations - not just single nucleotide polymorphisms." In some cases, larger genetic permutations involving hundreds or thousands of bases are responsible for genetic disease.

Genomic Vision thus expects large permutations of over 1,000 bases to be as common as SNPs in contributing to pathological malfunction of various genes. As a result, Bensimon expects the technologies to co-exist as...

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