Genomic Vision: Combing stretched DNA

Identifying the genetic basis of disease is only partially addressed by SNP genotyping technologies. Genomic Vision S.A. has developed a complementary technology, dubbed Molecular Combing, that can visualize multiple whole genomes and quantitatively identify DNA substitutions of 1,000 or more bases.

According to Aaron Bensimon, co-founder, chairman and CEO, "more and more data is surfacing showing that polymorphisms are caused by larger permutations - not just single nucleotide polymorphisms." In some cases, larger genetic permutations involving hundreds or thousands of bases are responsible for genetic disease...