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Cytopia: '(J)ust (A)nother (K)inase'

October 28, 2002 8:00 AM UTC

When Andrew Wilks discovered a new group of kinases in 1989 while looking for cytokine receptors, he wanted to call them JAK kinases for "just another kinase," because they weren't what he was looking for. Indeed, cytokine receptors have no intracellular kinase domain.

"I chickened out," Wilks said. Instead, JAK refers to Janus kinases, because members of that family have two kinase domains. ...