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Johns Hopkins University School of Medicine other research news
May 17, 1999 7:00 AM UTC
Johns Hopkins researchers and colleagues published in the Proceedings of the National Academy of Sciences that mice lacking PARP are resistant to neurotoxicity that results from administration of the neurotoxin MPTP, which causes Parkinson's disease-like symptoms. Mice lacking PARP had previously been shown to be resistant to neuronal damage following stroke (see BioCentury, Oct. 13, 1997). The researchers suggested that PARP inhibitors may have therapeutic benefit in Parkinson's disease. ...