Rigel Inc. other research news

Rigel researchers and colleagues published in Immunity the identification of toso, an integral membrane protein expressed in lymphoid cells that inhibits the apoptosis of T cells mediated by Fas and members of the TNF receptor family. The researchers suggested that toso could be used to prevent cell death of unactivated T cells, or to induce apoptosis of T cells in autoimmune diseases or transplantation. They also suggested that toso may play a role in regulating cell death in cancer cells. ...