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Columbia University other research news
August 26, 1996 7:00 AM UTC
University researchers published in Nature their identification of the class A scavenger receptor (SR), found on microglia cells in the brain, as a possible therapeutic target in Alzheimer's. The receptor contains a collagen-like region that is similar to the region on the complement protein C1q, which binds beta-amyloid. A synthetic peptide mimicking this domain blocked the adhesion of cells that express the SR, including microglia, to collagen IV. ...