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Feb 27, 2012
 |  BC Week In Review  |  Clinical News  |  Preclinical Results

Exelixis preclinical data

Researchers at the University of California, San Francisco, Pfizer Inc. (NYSE:PFE, New York, N.Y.) and Exelixis reported data from mouse models of pancreatic cancer showing that simultaneous inhibition of c-Met and VEGF signaling reduced tumor invasiveness and metastasis, whereas inhibiting VEGF signaling alone increased invasion and metastasis of tumors. Specifically, mice with pancreatic...

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