BioCentury
ARTICLE | Clinical News

Conatus' emricasan misses in Phase IIb in liver transplant patients

April 6, 2018 2:51 PM UTC

Conatus Pharmaceuticals Inc. (NASDAQ:CNAT) said emricasan missed the primary endpoint of improving fibrosis in the Phase IIb POLT-HCV-SVR trial in post-orthotopic liver transplant recipients with fibrosis or cirrhosis.

The trial enrolled 51 patients whose transplanted livers were damaged by recurrent HCV infection. The patients subsequently achieved a sustained virologic response (SVR) following HCV therapy, but their transplanted livers had residual fibrosis or cirrhosis...

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