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May 20, 2013
 |  BC Week In Review  |  Clinical News  |  Clinical Results

MPDL3280A: Phase I data

Data from 140 patients with locally advanced or metastatic solid tumors whose disease had progressed despite prior therapy in an open-label, dose-escalation, international Phase I trial showed that IV MPDL3280A once every 3 weeks led to an ORR of 21%. Responders included patients with non-small cell lung cancer (NSCLC), melanoma, renal cell carcinoma (RCC), colorectal cancer and gastric cancer. Roche's Genentech Inc. unit said that 26 of the 29 responders are continuing to...

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