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May 13, 2013
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Tamibarotene: Phase IIb discontinued

CytRx discontinued a double-blind, international Phase IIb trial in 140 patients with stage IIIb/IV NSCLC after an interim analysis showed that first-line treatment with twice-daily oral tamibarotene plus paclitaxel and carboplatin was unlikely to meet the primary endpoint of improving PFS vs. placebo plus paclitaxel and carboplatin. CytRx made the decision based on a recommendation from the study's independent DSMB....

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