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Nov 19, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Humira adalimumab: Additional Phase III data

Additional data from the double-blind, international Phase III ABILITY-1 trial in 179 patients with active non-radiographic axial spondyloarthritis showed that Humira significantly improved Health Assessment Questionnaire for Spondyloarthropathies (HAQ-S) scores at week 12 vs. placebo (reductions of 0.3 vs. 0.1 points, p=0.025). Humira also significantly improved SF-36 physical component summary scores at week 12 vs. placebo (5.5 vs. 2 points, p<0.001).

A post hoc analysis of the open-label extension study of the ABILITY-1 trial showed that 62% patients receiving Humira met the minimum important difference...

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