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Nov 12, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

AMG 145: Phase II data

The double-blind, international Phase II RUTHERFORD trial in 168 patients with heFH on a stable dose of statin therapy with or without ezetimibe showed that 350 and 420 mg doses of subcutaneous AMG 145 given every 4 weeks each met the primary endpoint of reducing LDL-C from baseline to week 12 vs. placebo (43% and 55% vs. a 1% increase,...

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