12:00 AM
Nov 12, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

AMG 145: Phase II data

The double-blind, international Phase II LAPLACE-TIMI 57 trial in 631 patients on a stable dose of statin therapy with or without ezetimibe showed that all doses of subcutaneous AMG 145 met the primary endpoint of reducing LDL-C from baseline to week 12 vs. placebo. Specifically, AMG 145 given every 2 weeks led to mean reductions in LDL-C...

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