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Sep 17, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Synavive: Development discontinued

Zalicus discontinued development of Synavive after the double-blind, international Phase IIb SYNERGY trial in 259 patients with moderate to severe RA showed that the compound missed the secondary endpoint of reducing DAS28-CRP scores from baseline to week 12 vs. 2.7 mg prednisolone, the active glucocorticoid component of Synavive (0.9 vs. 1.125 points). Synavive did meet the primary endpoint of...

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