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Sep 17, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Resminostat: Additional Phase II data

Additional data from the open-label, German and Italian Phase II SHELTER trial in 45 patients with HCC refractory to Nexavar sorafenib showed that second-line treatment with resminostat in combination with Nexavar (n=26) produced a median OS of 8 months, while median OS for patients receiving resminostat alone was 4.1 months (n=19). 4SC said it believes the 8 month median OS in the combination arm is the highest median OS achieved in clinical studies of new therapies for second-line HCC. The result also appears to be an almost 3-month improvement...

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