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Sep 10, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Spiriva HandiHaler tiotropium: Additional Phase IIIb data

A retrospective analysis of a subgroup of 2,012 low-risk patients with moderate to severe COPD in the double-blind, international Phase IIIb UPLIFT trial showed that Spiriva HandiHaler tiotropium significantly reduced mean annual rate of exacerbations over the 4-year trial by 28% vs. placebo (0.43 vs. 0.61; p<0.0001). Compared to placebo, Spiriva significantly reduced the time to first exacerbation by 24% and St. George's Respiratory Questionnaire (SGRQ) total score at 4...

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