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May 21, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Zytiga abiraterone acetate: Phase II data

An open-label, U.S. Phase II trial in 58 men with localized high-risk prostate cancer who were candidates for radical prostatectomy showed that neoadjuvant therapy with Zytiga plus leuprolide and prednisone for 24 weeks prior to surgery led to a pathological CR in 3 of 29 patients (10%) vs. 1 of 27 patients (4%) who received leuprolide alone for 12 weeks followed by Zytiga plus leuprolide and prednisone for an additional 12 weeks...

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